If you no longer have the leaflet that came with your medicine, you can search for an online version of it using our medicines A to Z.

first-generation antihistamines (also known as sedating antihistamines because they all cause drowsiness) Rare: hepatic function abnormal (increased transaminases, alkaline phosphatase, γ-GT and bilirubin) The apparent volume of distribution is 0.50 l/kg. Plasma protein binding of cetirizine is 93 ± 0.3 %. Cetirizine does not modify the protein binding of warfarin.

Children aged 2 and over can take cetirizine liquid bought from pharmacies or prescribed by their doctor. Tell your doctor or pharmacist if you are taking, have recently taken or might take any othermedicines. There are a reasonably wide range of different types of antihistamines available for dogs, some of which have different active ingredients and dosage levels, and your vet will work out which one is likely to prove to be the best fit for your dog.

Antihistamines are medicines often used to relieve symptoms of allergies, such as hay fever , hives , conjunctivitis and reactions to insect bites or stings . Antihistamine tablets and liquids are available over the counter from a pharmacy without the need for a prescription. Antihistamine nasal sprays are only available on prescription. Antihistamines can be used on their own for mild cases of hay fever, or with other products. Your GP or pharmacist can advise you on what treatments are most suitable for you. allacan was not mutagenic in the Ames test, and not clastogenic in the human lymphocyte assay, the mouse lymphoma assay, and in vivo micronucleus test in rats .If your hay fever symptoms are really bad, you may occasionally need short-term relief. If this is the case, your GP may prescribe a short course of steroid tablets lasting between five to 10 days. The steady - state peak plasma concentration is approximately 300 ng/ml and is achieved within 1.0 ± 0.5 h. The distribution of pharmacokinetic parameters such as peak plasma concentration (C max) and area under curve (AUC), is unimodal in human volunteers. Your vet may take skin scrapings, blood samples and run other diagnostic tests, as well as potentially running exposure testing on your dog to get to the bottom of what is causing their allergy to flare up in the first place.

If you have ongoing hay fever symptoms that aren't relieved by any of the usual treatments, your GP may refer you to an allergy specialist for further investigation and treatment.

Taking antihistamines with other medicines, food or alcohol

In a placebo-controlled study, cetirizine given at the high daily dose of 60 mg for seven days did not cause statistically significant prolongation of QT interval.