Only mild side effects were reported. Only 4 women in the study showed slight virilization changes, despite being given huge doses. Such side effects also reversed after they stopped taking Anadrol. This is also what we see anecdotally among our female patients. As a DHT derivative, oxymetholone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites. [4] However, uniquely among DHT derivatives, oxymetholone is nonetheless associated with relatively high estrogenicity, and is known to have the potential to produce estrogenic side effects such as gynecomastia (rarely) and water retention. [4] [16] [17] [18] It has been suggested that this may be due to direct binding to and activation of the estrogen receptor by oxymetholone. [4] Oxymetholone does not possess any significant progestogenic activity. [4] Pharmacokinetics [ edit ] In another study, women were given Oxymetholone to treat anemia and bone marrow failure ( 20). They started on a dose of 1mg per kg, then it increased in monthly increments by 50%, up to 100mg per day. Every female was given a dose of at least 50mg of Anadrol per day. Anadrol-50 is often used by men to treat anemia or to gain muscle mass. However, it’s important to note that the use of Anadrol-50 can lead to some unwanted side effects in men, including:

Those who are planning on cycling Anadrol should try and minimize this spike in BP, by performing regular cardio ( 14). We find this improves blood flow notably to and from the heart.Anadrol can be used on a cut to increase fat burning, help retain muscle tissue and dramatically increase muscle fullness. It’s important to note that Anadrol-50 is not recommended for pregnant or breastfeeding women. A woman considering this drug must talk to her doctor about the potential risks and benefits. Understanding the Risks When taking Anadrol-50, it is vital to understand the potential risks associated with the medication. While it can effectively treat certain types of anemia, it is not without its dangers. Here are some essential things to keep in mind: Warnings ANADROL® ( oxymetholone) Tablets for oral administration each contain 50 mg of the steroid oxymetholone, a potent anabolic and androgenic drug. With Anadrol, the conversion of DHT isn’t through the usual pathway, being the 5-alpha reductase enzyme.

Anadrol-50 may increase the risk of bleeding when taken with warfarin. You must inform your doctor if you are taking warfarin or any other blood thinners before starting Anadrol-50. Protein Synthesis and Nitrogen Retention Anadrol-50 (Oxymetholone) is a steroid I’ve only used on a couple occasions in the past and for me personally, I didn’t like it nearly as much as Dbol. We have had patients drink 250ml of grapefruit juice every 12 hours, which kept CYP3A4 consistently deactivated throughout the day. Also on Anadrol, the blood becomes more viscous due to a dramatic rise in red blood cell count. Consequently, blood flow becomes impeded, making it easier to get out of breath. These impressive results are typical after a few cycles of Anadrol. Are Anadrol’s Results Permanent?In comparison, Winstrol binds strongly to SHBG and consequently produces strong masculine side effects in women. Winstrol also does not convert into estrogen, creating an optimal environment for virilization. Kicman AT (June 2008). "Pharmacology of anabolic steroids". British Journal of Pharmacology. 154 (3): 502–21. doi: 10.1038/bjp.2008.165. PMC 2439524. PMID 18500378. Anadrol-50 can also cause rapid weight gain, which can concern some individuals. While this weight gain can benefit those looking to build muscle, it can also be a sign of fluid retention or other underlying health issues. Monitoring your weight and talking to your doctor if you experience rapid weight gain is crucial.

Abuse of Anadrol, or other steroids, may also lead to infertility; due to decreased sperm count and quality. In our experience, this effect can become permanent, preventing men from having children ( 16). Also, there is not much benefit to doing this, as gains will plateau, due to your body adapting to the steroid. Presented most commonly as a 50mg tablet, oxymetholone has been said to be one of the "strongest" and "most powerful" AAS available for medical use. [4] [13] Similarly, there is a risk of side effects. [14] [15] Oxymetholone is highly effective in promoting extensive gains in body mass, mostly by greatly improving protein synthesis. [4] For this reason, it is often used by bodybuilders and athletes. [4] Non-medical uses [ edit ] When taking Anadrol-50, being aware of potential interactions with other substances is vital. Here are some substances that may interact with Anadrol-50: Iron Supplements We find that consuming tea, coffee, energy drinks or pre-workout supplements also negatively impacts sleep, due to the caffeine content ( 33). Thus, avoiding or decreasing the number of stimulants in a person’s diet will help. Anadrol Summary: Pros vs Cons ProsAnadrol 50 is available in tablet form, with each tablet containing 50mg of Oxymetholone. The tablets are usually taken orally, with a glass of water. It’s recommended to take pills with food to help prevent stomach upset. In another study, 31 elderly men took 50-100mg per day for 12 weeks. The 50mg did not experience any increase in liver enzymes, however, the 100mg group experienced modest ALT and AST elevation ( 8). Although the 100mg group did not result in any cases of hepatic enlargement or cholestasis. This PCT was created by Dr. Michael Scally, a hormone replacement expert. This trio of drugs has been effective in treating 19 men with low testosterone levels (from the use of anabolic steroids). I know a lot of guys who have gained up to 30 lbs in just one month on Anadrol-50, but I don’t remember gains like that when I used it a long time ago. I know they say that when it comes to size and strength that Anadrol is the king, but like I said I felt like I got more out of Dianabol.