Third - consistency is key. It takes awhile to work out the right strategy for achieving the results you’re after, and if you’re not willing to put up the budget to keep the practice up for the long-haul, you might be better off not trying this one at all. Most valuably, the Visia scanning unit was not with out direct justification for this drastic improvement - and we’re going to look into the details as to what changed to create this improvement. RD: I think the big one because everybody looks at my skin, I have my skin routine down pat but what can throw me with my skin is hormones. Using OS-01, you can promote skin rejuvenation in a more effective way - from the inside out, instead of the outside in and without the side effects of retinols (redness, dryness, skin sensitization and so on).

Once you have senescent cells, there is a cascade of inflammatory signals leading to events such as collagen breakdown, which in turn will lead to a series of further dysfunctions in the skin. While there was likely an impact on the wrinkle algorithm from change in facial angle, it is very unlikely that this the source of such dramatic improvement. So “topical supplement”, basically means a product that's designed to optimize the health of the skin. If the product really can reduce your skin’s biological age, then you might just make this investment. Based on our interview with Dr Reis in February, we’d expect there would be observable improvements in skin texture.Secondly, this concept of “ skinspan”, which sounds closely related to healthspan. These are new concepts to our readers- tell us about them. Our verdict continues to be that OneSkin OS-01 not only works, but is an essential part of your longevity strategy for your skinspan.

Consider that your skin is your largest organ, and it plays a very important role in overall bodily wellness and longevity, much beyond how you look. LB: Wow, that's really interesting to hear that it's been created or discovered, in a way. What an amazing discovery to find a small molecule that can penetrate the skin, get into the cell and then activate the telomerase gene.

Pleased With Everything

Telomere dysfunction is now known to be one of the causes of aging. Within the skin, increasing amounts of evidence are linking telomere ‘attrition’ (shortening) to skin aging, but more research is needed to demonstrate the direct link between telomerase and improved skin health. LB: That's a grand vision and will get our readers very excited. You just talked about skin aging, hair loss, fat tissue, and these being driven by cellular senescence. This all fits into a bigger picture for longevity technologies over the next decade and more. CR: Every tissue in our body has its own biological age, which is often different from our chronological age. Depending on your genetics, on your lifestyle, you can have a higher or lower biological age compared to your chronological age. Our current algorithm is called MolClok, which we trained with more than 500 samples of skin from which we know the chronological age. Clinical trials support the use of One Truth 818 which is proven to slow down the ageing process and significantly reverses the appearance of wrinkles, lines and loss of elasticity.