For both kinds of spinosad liquid spray, you should apply it to the tops and bottoms of the leaves as well as on stems. You should spray it wherever you see pests and larvae. Remember, avoid spraying flowers to keep the bees safe, and avoid spraying the soil if you can. You can spray larvae directly, but it’s when they eat sprayed leaves that you’ll find it to be the most effective. If you see eggs on your plants, you’ll need to spray again in a few days after the eggs have hatched. a b c Sparks T, Dripps JE, Watson GB, Paroonagian D (6 November 2012). "Resistance and cross-resistance to the spinosyns- A review and analysis". Pesticide Biochemistry and Physiology. 102: 1–10. doi: 10.1016/j.pestbp.2011.11.004 . Retrieved 17 November 2011.

Merchant M. "Safer Flea Control | Insects in the City". Texas A&M AgriLife Extension Service . Retrieved 20 October 2012.Hot pepper sprays also can deter feeding by spider mites, aphids, and pesky animals, but have limited impact on larger garden insects. The same tiny insects are impacted by neem, so sprays that contain both capsaicin and neem can be extremely useful against aphids, whiteflies and spider mites in a greenhouse, where natural predators are in short supply. When used carefully, organic insecticides do not threaten spiders and other important natural predators There are more benefits to using spinosad than there are dangers, so you’ll probably want to keep this insect killer on hand if you don’t already. CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C=C[C@H]3[C@@H]2CC(=O)O1)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C.CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C(=C[C@H]3[C@@H]2CC(=O)O1)C)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C

So, how does this wonder product work? Saccharopolyspora spinosa is toxic to pests and affects their nervous systems. Once spinosad is applied to the plant, insect larvae will feed on the substance and will die within a day or two. Spinosad will cause the insect’s muscles to flex uncontrollably, which leads to paralysis and eventually death. It’s most effective when the larvae eat it, but simply walking over it is usually enough to do some damage. Comfortis, a prescription flea-only medication, eliminates fleas before they have the opportunity to create eggs and maintains efficacy for an entire month with every dose. Buy flea treatment for dogs tablets here at UK Pet Drugs. comfortis RTU spinosad sprays are the easiest to use in home gardens because you can begin spraying it as soon as you open the bottle. It won’t require any mixing or measuring, but you should still read the label of your RTU product to make sure you use it correctly. vaginal bleeding, more difficult labors, and abortions were also observed in some pregnant animals at the highestCrouse GD, Sparks TC, Schoonover J, Gifford J, Dripps J, Bruce T, etal. (February 2001). "Recent advances in the chemistry of spinosyns". Pest Management Science. 57 (2): 177–185. doi: 10.1002/1526-4998(200102)57:2<177::AID-PS281>3.0.CO;2-Z. PMID 11455648. Like many other chemicals, spinosad can have some side effects on certain people. High exposure to the spray can cause some people to suffer from skin redness and irritation of the area exposed to the insecticide. Insecticides can be quite toxic for humans and animals alike and most often would end up in our food, but one natural insecticide stands out among the group. That insecticide is spinosad.