Easy to Use: Each box of regelle contains either 3, 6 or 12 individual Applicators The applicator is simply inserted into the vagina, squeezed, then removed and discarded. The single use applicator delivers moisture where it is needed. Gelfand, M et al (1994) Treating Vaginal Dryness in Brest Cancer Patients: Results of Applying a Polycarbophil Moisturizing Gel. Journal of Women’s Health; volume 3, Number 6, p427-433# Furthermore, polycarbophil and carbopol are substances with a buffering action and their use in women experiencing menopause either naturally or as a result of surgery has led to a correction of the vaginal pH values comparable to those obtained with hormone replacement therapy 4. Regelle comes in pre-filled hygienic single use applicators. The applicator is simply inserted into the vagina, squeezed, then removed and discarded. The single use applicator delivers moisture where it is needed.

Regelle coats the entire vaginal passage and provides immediate relief to dry cells. Once in place, Regelle delivers continuous moisture for up to 3 days per single application (as the purified water is gradually released from the polycarbophil, dry tissues are rehydrated). Dry cells are then shed naturally, leaving healthier and more supple skin beneath. I found Regelle very easy to use I found Regelle easy to use I found Regelle difficult to use I found Regelle very difficult to use No opinion 8. Where would you buy Regelle? Regelle works by lining the inside of the vagina, providing moisturisation, lubrication and comfort 1. Regelle is a water-based intravaginal gel that is clinically proven to provide soothing, continuous moisture, giving relief from symptoms of vaginal dryness, atrophy, itching, irritation and discomfort. Regelle is a NON-hormonal preparation and can be used in conjunction with systemic hormone replacement therapy (HRT).Regular use of Regelle, once every 3 days, can help maintain vaginal health and comfort by replenishing essential vaginal moisture before and after menopause.The polycarbophil-carbopol based vaginal gel has a high level of bio-adhesiveness capable of ensuring a prolonged moisturising action on the epithelium of the vaginal mucous membrane 2. This gel is capable of adhering to the vaginal mucous membranes thanks to the presence of two characteristic polyacid polymers having a high molecular weight and a molecular structure very similar to that of the vaginal mucous: Polycarbophil and carbopol 2. Polycarbophil is hydrophilic and provides direct cellular ‘moisturising’ action resulting from an increased flow of water molecules from outside to the inside of the cells on the surface of vaginal mucous membrane. This action creates a moist film over the vaginal wall hydrating the underlying mucosa 3. This movement of water into the cells of the vaginal epithelium is promoted by the particular unique structure of the polymers in this gel 2. Being bio-adhesive, Regelle has been shown in laboratory and clinical studies to adhere to tissue for 24-72h, resulting in diffusion of water from the gel to the underlying vaginal mucosa 3. Can be use with HRT: Regelle is also suitable for use by patients taking systemic Hormone Replacement Therapy (HRT). Opting for Regelle, which is a long-lasting vaginal moisturiser is the perfect choice for women seeking a non-hormonal solution to vaginal dryness providing continuous moisturisation for up to 3 days after each application, unlike short acting lubricants.” Regelle is vaginal moisturiser, clinically proven to provide immediate relief from dryness and discomfort. Gelfand, M et al (1994) Treating Vaginal Dryness in Brest Cancer Patients: Results of Applying a Polycarbophil Moisturizing Gel. Journal of Women’s Health; volume 3, Number 6, p427-433

Bachmann, G.A et al (1992) Long Term Nonhormonal Treatment of Vaginal Dryness. Clinical Practice in Sexuality; Volume 8, Number 8/9, p 3-8 Healthcare Professional e.g. Pharmacist, GP Through a friend From an advert Internet Other 3. Prior to using Regelle, what were your symptoms? (Dryness, pain or discomfort during intercourse etc..) In a 12 month study by Bachmann et al of peri-menopausal and post-menopausal women, use of polycarbophil gel 3 times per week for one year showed that not only had vaginal health improved but this improvement was maintained as long as subjects were using the vaginal product. All parameter of the vaginal health index showed improvement including vaginal moisture, vaginal fluid volume, vaginal pH, vaginal epithelial integrity and vaginal elasticity. Overall the gel was found be well tolerated and effective in improving overall vaginal health for one year of continuous use. There were no patients who dropped out due to adverse events.Maintenance therapy can be achieved with a three times weekly application. Depending on the level of dryness, Regelle ® can be used more or less frequently and can be used daily. Rejuvenates: Regelle also improves the elasticity of the vaginal wall, encourages the return of natural secretions and restores the natural pH of the vagina. Wear breathable cotton underwear and loose clothing until symptoms improve. Do not use soaps, shower gels, bath oils or disinfectants to cleanse the vaginal area. Use Regelle for long lasting immediate relief. Nachtigall, L.E (1994) Comparative study: Replens versus local estrogen in menopausal women. Fertility and Sterility.Volume 61, Number 1, p 178-180.

A recent survey of 500 women in Ireland reported 7 out of 10 experience the painful debilitating effects of vaginal dryness at some stage. However, 59% of sufferers do not seek help from their GP or healthcare professional. Almost 20%, quoted embarrassment as a factor in not seeking help, and a further 13% assumed their condition would go away. Garg et al (2001) Properties of new acid buffering bioadhesive vaginal formulation. Contraception 64. 67-75. In a study by Gelfand et al (1994) treating vaginal dryness in breast Cancer Patients Polycarbophil Moisturising gel show that a polycarbophil vaginal moisturiser gel effectively relieves vaginal dryness in most patients without causing significant side effects. This study also showed a statistically significant reduction in mean vaginal pH and improvement in overall vaginal elasticity scores, as well as significant improvement in vaginal health measures at each monthly interval.

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Regelle ® delivers continuous moisture, which the cells absorb, causing them to regain their natural structure and elasticity. For many women, vaginal dryness is a common problem that affects and interferes with their day-to-day lives. Vaginal dryness can occur at any age. Women may experience dryness during the menopause, times of stress or as a side effect of certain medications and medical treatments. The effects of vaginal dryness vary from woman to woman, ranging from minor discomfort to painful sexual intercourse. Regardless of the level of discomfort, vaginal dryness can impact your daily life. of sufferers said this common condition affects their confidence, while, for 41% of women, vaginal dryness causes painful sex, and 45% said they avoid sex altogether.