http://www.arthritis.org/living-with-arthritis/treatments/natural/supplements-herbs/guide/indian-frankincense.php In animal models, boswellia had an anti-inflammatory and antioxidant effect, which appeared to protect neurons in the brain and improve motor function in a rat model of Parkinson’s disease. The authors of a 2019 study suggested that an active extract of boswellia may help reduce inflammation in people with RA. However, this study used rats, so the results may not apply to humans.

A recent study in the journal Oncotarget also found that the essential oil from boswellia impaired aggressive skin cancer cells without harming healthy skin cells. However, the researchers used cells and animal models. The people of the ancient world were right to believe Boswellia had benefits for health and wellness. Here’s what modern science has to say how Boswellia enhances health: The following sections discuss the evidence behind its potential benefits for inflammatory health conditions. Rheumatoid arthritis

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Ammon HP. Boswellic acids and their role in chronic inflammatory diseases. Adv Exp Med Biol. 2016;928:291–327. doi:10.1007/978-3-319-41334-1_13 Gomaa AA, Mohamed HS, Abd-Ellatief RB, et al. Boswellic acids/ Boswellia serrata extract as a potential COVID-19 therapeutic agent in the elderly. Inflammopharmacology. 2021;29(4):1033-1048. doi:10.1007/s10787-021-00841-8 Khan, M. A., et al. (2016). Pharmacological evidences for cytotoxic and antitumor properties of boswellic acids from boswellia serrata [Abstract]. Yu G, Xiang W, Zhang T, Zeng L, Yang K, Li J. Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis. BMC Complement Med Ther. 2020;20(1):225. doi:10.1186/s12906-020-02985-6

Soni KK, et al. (2015). Boswellia serrata and Ocimum sanctum extractsreduce inflammation in an ova-induced asthma model of BALB/c mice. DOI: Boswellia appears to be effective in reducing inflammation, so it may also lessen the symptoms of RA. Gupta I, Parihar A, Malhotra P, et al. Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta Med. 2001;67(5):391-395. doi:10.1055/s-2001-15802. Roe AL, Wilcox R, Price JM, et al. An evaluation of potential inhibition of CYP3A4/5 and CYP2C9 enzymatic activity by Boswellia serrata extract. Applied In Vitro Toxicology. 2019; 5(1) doi.org/10.1089/aivt.2018.0023 Photoaging is a type of premature ageing caused by overexposure to UV rays. Topical application of Boswellia has been shown to reduce the appearance of sun damage on the skin. 6 How to use BoswelliaMany retailers, both online and in stores, will sell the resin in capsules. It may occasionally be possible to buy the raw resin, which has a hard texture similar to that of sap. People may extract active ingredients, such as boswellic acids, from the resin and add them to a capsule or tablet. In this animal model, the anti-inflammatory effect of boswellia was less significant than that of a standard prescription medication called indomethacin. However, the researchers noted that the extract might be useful as a complementary therapy to support traditional RA treatment. Cancer and cancer therapy In the future, this may make boswellia a helpful complementary treatment for asthma. For now, researchers need to focus on working toward studies in humans. Parkinson’s disease Kumar, R., et al. (2019). Effect of boswellia serrata extract on acute inflammatory parameters and tumor necrosis factor-α in complete Freund's adjuvant-induced animal model of rheumatoid arthritis. Haroyan A, Mukuchyan V, Mkrtchyan N, et al. Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study. BMC Complement Altern Med. 2018;18(1):7. Published 2018 Jan 9. doi:10.1186/s12906-017-2062-z.

A 2016 review paper reports that boswellic acids might have antitumor properties and be toxic to cancerous cells. The authors conclude that this could make them helpful in future cancer treatments, though clinical trials are necessary to confirm this. Kimmatkar N, etal. (2003). Efficacy and tolerability of Boswelliaserrata extract in treatment of osteoarthritis of knee - a randomized double blind placebo controlled trial[Abstract]. DOI: Park B, et al. (2011). Acetyl-11-keto-β-boswellic acidsuppresses invasion of pancreatic cancer cells through the downregulation ofCXCR4 chemokine receptor expression [Abstract]. DOI: Grover AK, et al. (2016). Benefits of antioxidantsupplements for knee osteoarthritis: rationale and reality. DOI:Vishal AA, et al. (2011). A double blind, randomized, placebo controlledclinical study evaluates the early efficacy of Aflapin in subjects withosteoarthritis of knee. DOI: Boswellic acid may also have a role in asthma treatment. Research findings have shown that boswellic acid suppresses inflammation in the airways and inhibits the secretion of cytokines, which are markers that lead to inflammation. Chopra A, et al. (2000). Randomized double blind trial of an Ayurvedicplant derived formulation for treatment of rheumatoid arthritis [Abstract].

The Arthritis Foundation recommend boswellic acid capsules as a potential therapy for RA, as well as for osteoarthritis. The Arthritis Foundation recommend taking approximately 300–400 milligrams (mg) of boswellia three times per day to deliver boswellic acids to the body. They recommend looking for capsules that contain 60% boswellic acid, as it is the active ingredient.Natural Standard. (2010). Natural standard herb & supplement guide - e-book:An evidence-based reference. Maryland Heights, MO: Mosby.